Cardiovascular benefits of magnesium are similar to statin pharmaceuticals

A review published in the October 2004 issue of the Journal of the American College of Nutrition has found that many cardiovascular benefits of magnesium parallel those of statin drugs. Statins are a class of drugs commonly prescribed for individuals with elevated cholesterol levels, a risk factor for cardiovascular disease.

The researchers discuss the fact that both statin drugs and magnesium can inactivate the enzyme responsible for the first step in cholesterol formation and improve the function of blood vessels, reduce inflammation, and provide other cardiovascular benefits. Magnesium, however, is also involved in the activity of another enzyme known as LCAT, which helps elevate beneficial HDL cholesterol levels while reducing unhealthy LDL cholesterol and triglycerides. In addition, magnesium is necessary for the enzyme that converts linoleic acid and linolenic acid into compounds that reduce inflammation. Furthermore, optimal levels of magnesium within the cell are a natural calcium channel blocker, which helps dilate the blood vessels.

Because of its many cardiovascular benefits, relatively low cost, and good safety profile, the researchers suggest that increasing magnesium could be a viable alternative for those who cannot or choose not to take statin drugs.

Note: If you are currently taking a statin drug to lower cholesterol, do not discontinue its use except on the advice of your physician. This information is not meant to imply that magnesium supplements should replace all statin drugs. However, adequate magnesium is very important for cardiovascular health, especially for those at risk for coronary artery disease.