Vitamins E and C confirmed safe by leading experts

In a new article published in the April issue of the American Journal of Clinical Nutrition, fourteen leading safety and antioxidant experts reviewed the available scientific literature on vitamin E and C and concluded that high dosages commonly used in supplements are safe for the general population.

In reviewing the available scientific literature on vitamins E and C, the scientists evaluated clinical trials as well as epidemiological studies in humans, including the recent, controversial meta-analysis on vitamin E from Johns Hopkins University. Based on the 95 studies analyzed, the experts determined there was sufficient information from human data to support a conclusion on safety. The experts concluded that evidence of potential adverse effects of high vitamin E intakes in humans is not convincing and that supplements appear safe for most adults in amounts up to 1,600 IU.

With regard to vitamin C, the authors noted that other than occasional gastrointestinal upset or mild diarrhea, there is no pattern of evidence to support concerns about safety in dosages commonly consumed.

Vitamins E and C are among the most popular dietary supplements. Many studies suggest that these antioxidant supplements, either alone or in combination with other supplements, can help promote overall good health and be helpful in lowering the risk of certain chronic degenerative diseases.

American Journal of Clinical Nutrition, Vol. 81, No. 4, 736-745, April 2005