Vitamin E and Respiratory Tract Infections
Four hundred fifty-one individuals aged 65 and older at 33 long-term care facilities completed a course of 200 IU of vitamin E per day or a placebo from April 1998 to August 2001. In addition, all of the subjects received a multi- vitamin that provided 50 percent of the recommended daily allowance for essential vitamins and minerals. The incidence of lower respiratory infections, such as acute bronchitis and pneumonia, and upper respiratory tract infections, including cold, influenza, sore throat, middle ear infection and sinusitis, was documented over the course of the trial.
The subjects who received vitamin E acquired fewer respiratory tract infections than those who did not receive the vitamin. Participants who received the vitamin experienced a 20 percent decreased risk of acquiring the common cold, which accounted for 84 percent of the upper respiratory infections reported. In addition, those taking vitamin E had fewer colds per person. Although vitamin E showed no significant effect on lower respiratory tract infections, the protective effect of vitamin E supplementation on upper respiratory tract infections observed in this group merits further investigation and suggests important implications for the well-being of the elderly.